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1,532 results

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CNTF and CNTF receptor alpha are constitutively expressed by astrocytes in the mouse brain.
Dallner C, Woods AG, Deller T, Kirsch M, Hofmann HD. Dallner C, et al. Glia. 2002 Mar 15;37(4):374-8. Glia. 2002. PMID: 11870876
Ciliary neurotrophic factor (CNTF) is regarded as one of the signals that lead to astrocyte activation following central nervous system lesion. However, it is not clear if CNTF can directly initiate astrocytic responses to injury because CNTF …
Ciliary neurotrophic factor (CNTF) is regarded as one of the signals that lead to astrocyte activation following …
Regional distribution, developmental changes, and cellular localization of CNTF-mRNA and protein in the rat brain.
Stöckli KA, Lillien LE, Näher-Noé M, Breitfeld G, Hughes RA, Raff MC, Thoenen H, Sendtner M. Stöckli KA, et al. J Cell Biol. 1991 Oct;115(2):447-59. doi: 10.1083/jcb.115.2.447. J Cell Biol. 1991. PMID: 1918150 Free PMC article.
Ciliary neurotrophic factor (CNTF) is a potent survival molecule for a variety of embryonic neurons in culture. ...In other brain regions both CNTF-mRNA and protein levels are much lower....
Ciliary neurotrophic factor (CNTF) is a potent survival molecule for a variety of embryonic neurons in culture. …
Permeability at the blood-brain and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF.
Poduslo JF, Curran GL. Poduslo JF, et al. Brain Res Mol Brain Res. 1996 Mar;36(2):280-6. doi: 10.1016/0169-328x(95)00250-v. Brain Res Mol Brain Res. 1996. PMID: 8965648

The plasma washout showed a decreasing plasma half-life in the order of brain-derived neurotrophic factor (BDNF) < neurotrophin-3 (NT-3) < ciliary neurotrophic factor (CNTF) < nerve growth factor (NGF). ...The Vp va

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The plasma washout showed a decreasing plasma half-life in the order of brain-derived neurotrophic factor (BDNF) < n

…
Vitronectin from brain pericytes promotes adult forebrain neurogenesis by stimulating CNTF.
Jia C, Keasey MP, Malone HM, Lovins C, Sante RR, Razskazovskiy V, Hagg T. Jia C, et al. Exp Neurol. 2019 Feb;312:20-32. doi: 10.1016/j.expneurol.2018.11.002. Epub 2018 Nov 6. Exp Neurol. 2019. PMID: 30408465 Free PMC article.
Unexpectedly, VTN inhibited FAK signaling and VTN-/- mice had increased FAK signaling in the SVZ. Further, an FAK inhibitor or VTN increased CNTF expression, but not in conditional astrocytic FAK knockout mice, suggesting that VTN increases CNTF through FAK inhibiti …
Unexpectedly, VTN inhibited FAK signaling and VTN-/- mice had increased FAK signaling in the SVZ. Further, an FAK inhibitor or VTN increased …
Neurotrophins and the regulation of energy balance and body weight.
Rios M. Rios M. Handb Exp Pharmacol. 2014;220:283-307. doi: 10.1007/978-3-642-45106-5_11. Handb Exp Pharmacol. 2014. PMID: 24668477 Review.
Complex interactions between the brain and peripheral tissues mediate the effective control of energy balance and body weight. ...Several neurotrophins, most notably brain-derived neurotrophic factor, have been implicated in the molecular and cellular …
Complex interactions between the brain and peripheral tissues mediate the effective control of energy balance and body weight. ...Sev …
Actions of CNTF and neurotrophins on degenerating motoneurons: preclinical studies and clinical implications.
Sendtner M, Dittrich F, Hughes RA, Thoenen H. Sendtner M, et al. J Neurol Sci. 1994 Jul;124 Suppl:77-83. doi: 10.1016/0022-510x(94)90187-2. J Neurol Sci. 1994. PMID: 7807152 Review.
Isolated embryonic chick and rat motoneurons have been used to identify neurotrophic factors and cytokines capable of supporting the survival of developing motoneurons. Such factors include ciliary neurotrophic factor (CNTF), which is present ph …
Isolated embryonic chick and rat motoneurons have been used to identify neurotrophic factors and cytokines capable of supporting the …
Neurotrophic factor control of satiety and body weight.
Xu B, Xie X. Xu B, et al. Nat Rev Neurosci. 2016 May;17(5):282-92. doi: 10.1038/nrn.2016.24. Epub 2016 Apr 7. Nat Rev Neurosci. 2016. PMID: 27052383 Free PMC article. Review.
Ironically, obese individuals have high levels of plasma leptin and are resistant to leptin treatment. Neurotrophic factors, particularly ciliary neurotrophic factor (CNTF) and brain-derived neurotrophic factor (BDNF), are a …
Ironically, obese individuals have high levels of plasma leptin and are resistant to leptin treatment. Neurotrophic factors, particul …
Neurotrophins as a reliable biomarker for brain function, structure and cognition: A systematic review and meta-analysis.
McPhee GM, Downey LA, Stough C. McPhee GM, et al. Neurobiol Learn Mem. 2020 Nov;175:107298. doi: 10.1016/j.nlm.2020.107298. Epub 2020 Aug 18. Neurobiol Learn Mem. 2020. PMID: 32822863
Neurotrophins are signalling molecules involved in the formation and maintenance of synapses in the brain. They can cross the blood-brain barrier and be detected in peripheral blood, suggesting they may be a potential biomarker for brain health and function. …
Neurotrophins are signalling molecules involved in the formation and maintenance of synapses in the brain. They can cross the blood- …
The Roles of Ciliary Neurotrophic Factor - from Neuronutrition to Energy Metabolism.
Guo H, Chen P, Luo R, Zhang Y, Xu X, Gou X. Guo H, et al. Protein Pept Lett. 2022;29(10):815-828. doi: 10.2174/0929866529666220905105800. Protein Pept Lett. 2022. PMID: 36065930 Review.
Ciliary neurotrophic factor (CNTF) is a pluripotent neurotrophic factor originally isolated from chicken embryo ciliary neurons. ...In addition to its role in the nervous system, CNTF regulates the balance of energy metaboli …
Ciliary neurotrophic factor (CNTF) is a pluripotent neurotrophic factor originally isolated from c …
1,532 results